Beyond the Proof-of-Concept: Manufacturing Breakthroughs in Stem Cell- Islet Replacement Therapy
Time: 10:00 am
day: Day One Morning
Details:
- Successfully developing a full suspension protocol to differentiate human pluripotent stem cells into functional, glucose-responsive, insulin-producing islet cells, demonstrating their potential to treat diabetes in preclinical models
- Moving from animals to treating dozens of patients in a trial, we present a scalable protocol using advanced suspension bioreactor technology to produce robust, reproducible, and large-scale GMP manufacturing processes
- Discussing key insights on how to design quality control measures to ensure that every batch of manufactured islets is pure, potent, functional, and safe
