Replacing the Brain’s Immune System: Novel Brain Conditioning Approaches to Support iPSC‑Derived Microglia Cell Therapies
- Microglia as both therapeutics and immunological gatekeepers
- Designing brain conditioning strategies to enable durable engraftment, drawing parallels to bone marrow transplantation while navigating CNS‑specific safety constraints
- Key preclinical lessons for advancing first‑in‑class brain cell therapies