Rewriting the Rules of Differentiation: Driving iPSC Fate Through Direct Nuclear Reprogramming with TFome

  • Leveraging transcription factors (TFs) to drive differentiation without relying on cellexternal cues
  • Achieving up to 99% efficiency in four days through a single-step, cost-effective approach
  • Integrating AI and high-throughout experimentation to discover key TFs for scalable, precision-driven differentiation