Integrative Approaches for Prime Editing Drug Discovery Across Diseases Indications Using iPSC-Derived Model Systems
Time: 11:45 am
day: Day Two Track A AM
Details:
- Prime Editing enables precise correction of upwards of 90% of all human pathogenic mutations. Prime Editing’s ability to precisely make large & small edits, insertions, and deletions without double strand breaks represents a potential curative approach for patients
- To advance the development of Prime Editing therapies we have established robust physiologically relevant high-throughput in vitro models that recapitulate disease pathology using iPSC derived systems across various indications
- We demonstrate that iPSC-derived models can be a powerful tool for Prime Editing drug discovery across disease indications.
